HTLV-II Neurological Disease Blood Test

What is HTLV-II-associated neurological diseases?

HTLV-II-associated neurological diseases are neurological complications caused by infection with Human T-Cell Lymphotropic Virus Type II, a retrovirus that infects immune cells. The condition is caused by the HTLV-II retrovirus, which can gradually damage the nervous system over time. The Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies Test with Confirmation is the most important test for diagnosis because it detects specific antibodies that confirm active infection with the virus.

RECOMMENDED TEST Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation
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What causes HTLV-II-associated neurological diseases?

HTLV-II-associated neurological diseases are caused by infection with Human T-Cell Lymphotropic Virus Type II (HTLV-II), a retrovirus that targets and infects immune cells in the body. The virus is primarily transmitted through blood contact, sexual intercourse, breastfeeding, or sharing needles. Once HTLV-II infects the body, it can persist for life and gradually affect the nervous system over time, though not everyone infected will develop neurological complications.

What is the best test for HTLV-II-associated neurological diseases?

The Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies Test with Confirmation is the most important test for HTLV-II-associated neurological diseases because it specifically detects antibodies produced by your immune system in response to HTLV-II infection. This comprehensive test uses a preliminary screening followed by confirmatory testing to ensure accurate results and properly differentiate between HTLV-I and HTLV-II infections. The presence of HTLV-II antibodies in your blood confirms active infection with the virus, which is essential for understanding your risk of developing neurological complications and establishing appropriate medical monitoring.

When should I get tested for HTLV-II?

You should get tested if you have received blood transfusions before 1988, have injected drugs or shared needles, have had unprotected sex with multiple partners, or were born to a mother with HTLV infection. Testing is also important if you experience unexplained neurological symptoms like muscle weakness, difficulty walking, bladder problems, or numbness in the limbs. Early detection through blood testing allows for proper medical monitoring and management even before significant neurological symptoms develop.

What are the symptoms of HTLV-II-associated neurological diseases?
Symptoms of HTLV-II-associated neurological diseases develop gradually and may include muscle weakness, particularly in the legs, difficulty walking or maintaining balance, and bladder or bowel dysfunction. You might also experience numbness or tingling sensations in your limbs, muscle stiffness or spasms, and progressive difficulty with fine motor tasks. Because these symptoms overlap with other neurological conditions and develop slowly over years, many people do not recognize them as related to HTLV-II infection until they become more pronounced.
Who is at risk for HTLV-II infection?
People at highest risk for HTLV-II infection include individuals who inject drugs or share needles, those who received blood transfusions or organ transplants before routine screening began in 1988, and people with multiple sexual partners or unprotected sex. Children born to infected mothers are at risk through breastfeeding, and individuals from endemic areas including certain Native American populations and parts of Central and South America have higher infection rates. Healthcare workers with needlestick injuries and people who have had tattoos or piercings with unsterilized equipment also face increased risk.
What happens if HTLV-II infection is left untreated?
If HTLV-II infection is left unmonitored, it can lead to progressive neurological deterioration including chronic myelopathy, which causes increasing difficulty with walking and mobility. Over time, untreated infection may result in permanent nerve damage, loss of bladder and bowel control, and significant disability affecting your quality of life. While not everyone with HTLV-II develops severe complications, the lack of monitoring means you miss opportunities for supportive treatments and interventions that can help manage symptoms and slow disease progression.
Can HTLV-II-associated neurological diseases be diagnosed with a blood test?
Yes, HTLV-II infection can be definitively diagnosed with a blood test that detects antibodies against the virus. The blood test uses enzyme immunoassay screening followed by confirmatory testing with Western blot or other methods to ensure accurate identification of HTLV-II antibodies. While the blood test confirms infection status, your doctor may also order additional neurological evaluations including spinal fluid analysis or imaging studies to assess the extent of neurological involvement and rule out other conditions.
How is HTLV-II-associated neurological disease treated?
Treatment for HTLV-II-associated neurological diseases focuses on managing symptoms and slowing disease progression since there is no cure for the viral infection itself. Your healthcare provider may prescribe corticosteroids or immunomodulatory medications to reduce inflammation in the nervous system, along with physical therapy to maintain mobility and muscle strength. Bladder dysfunction may be managed with medications or catheterization, while pain management, muscle relaxants for spasticity, and supportive care help maintain quality of life as the condition progresses.
How can I prevent HTLV-II infection?
You can prevent HTLV-II infection by avoiding sharing needles or drug injection equipment, practicing safe sex using condoms, and ensuring any blood transfusions or organ transplants come from screened donors. If you are pregnant and infected with HTLV-II, avoiding breastfeeding can prevent transmission to your baby, as formula feeding eliminates this risk. Healthcare workers should follow proper safety protocols to prevent needlestick injuries, and everyone should ensure tattoos and piercings are done with sterile, single-use equipment at licensed facilities.
What can I do at home to manage HTLV-II-associated neurological symptoms?
At home, you can manage HTLV-II-associated neurological symptoms by maintaining a regular exercise routine with low-impact activities like swimming or stationary cycling to preserve muscle strength and mobility. Implement safety modifications in your home such as grab bars in the bathroom, non-slip mats, and clear walkways to prevent falls as balance becomes more challenging. Stay well-hydrated, maintain a fiber-rich diet to help with bowel function, practice stress-reduction techniques, and keep regular appointments with your healthcare team to monitor progression and adjust management strategies as needed.
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Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation
Google reviews 505 reviews
$287 $224
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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