HTLV-II Neurological Disease Blood Test

What is HTLV-II-associated neurological disease?

HTLV-II-associated neurological disease is a rare condition that causes nerve damage, muscle weakness, coordination problems, and sensory disturbances. It is caused by infection with Human T-Cell Lymphotropic Virus Type II (HTLV-II), a retrovirus that attacks the nervous system. The Human T-Cell Lymphotropic Virus I, II Antibodies Test with Confirmation is the most important test for diagnosis because it detects antibodies against HTLV-II infection in the blood.

RECOMMENDED TEST Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation
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What causes HTLV-II-associated neurological disease?

HTLV-II-associated neurological disease is caused by infection with Human T-Cell Lymphotropic Virus Type II (HTLV-II), a retrovirus that invades and damages the nervous system. This virus is transmitted through blood contact, sexual transmission, or from mother to child during pregnancy or breastfeeding. Once HTLV-II enters the body, it infects T-cells and can trigger inflammation in the brain and spinal cord, leading to progressive nerve damage that causes muscle weakness, coordination problems, and sensory disturbances.

What is the best test for HTLV-II-associated neurological disease?

The Human T-Cell Lymphotropic Virus I, II Antibodies Test with Confirmation is the most important test for HTLV-II-associated neurological disease because it detects specific antibodies your immune system produces in response to HTLV-II infection. This comprehensive test includes both preliminary screening and confirmatory testing to distinguish between HTLV-I and HTLV-II infections, which is critical since they cause different symptoms. When combined with neurological symptoms like muscle weakness and coordination problems, a positive HTLV-II antibody result confirms the diagnosis and helps your doctor develop an appropriate treatment plan.

When should I get tested for HTLV-II-associated neurological disease?

You should get tested if you experience unexplained muscle weakness, difficulty walking or maintaining balance, numbness or tingling in your legs or feet, or progressive coordination problems. Testing is especially important if you have risk factors like receiving blood transfusions before 1988 (when screening began), having shared needles, or being from an area where HTLV-II is more common. Early detection through blood testing allows you to start monitoring and treatment before nerve damage becomes severe.

What are the symptoms of HTLV-II-associated neurological disease?
HTLV-II-associated neurological disease causes progressive muscle weakness, particularly in the legs, making walking increasingly difficult. You might experience coordination problems, difficulty with balance, stiffness in your legs, and numbness or tingling sensations in your feet and lower legs. Some people develop bladder control issues, sexual dysfunction, or back pain. These symptoms typically develop gradually over months or years as the virus causes ongoing damage to the nervous system.
Who is at risk for HTLV-II-associated neurological disease?
People at higher risk include those who received blood transfusions or organ transplants before 1988, injection drug users who shared needles, individuals who had unprotected sex with an infected partner, and babies born to mothers with HTLV-II infection. The virus is more common among certain populations including Native American and indigenous communities in North and South America. Healthcare workers exposed to infected blood and people with multiple sexual partners also have increased risk of HTLV-II infection.
What happens if HTLV-II-associated neurological disease is left untreated?
Untreated HTLV-II-associated neurological disease causes progressive and irreversible nerve damage that worsens over time. You may lose the ability to walk independently and require a wheelchair or other mobility aids. Bladder and bowel control problems can develop, leading to infections and complications. The muscle weakness and sensory loss become more severe, significantly impacting your quality of life and independence. While the progression varies, early diagnosis and monitoring help manage symptoms and slow the advancement of nerve damage.
Can HTLV-II-associated neurological disease be diagnosed with a blood test?
Yes, HTLV-II-associated neurological disease is diagnosed primarily through blood tests that detect antibodies against the HTLV-II virus. The antibody test identifies whether you have been infected with HTLV-II by measuring your immune system response to the virus. A preliminary screening test detects the presence of antibodies, and then a confirmatory test distinguishes between HTLV-I and HTLV-II infections. When positive antibody results are combined with characteristic neurological symptoms, doctors can confidently diagnose HTLV-II-associated neurological disease.
How is HTLV-II-associated neurological disease treated?
Treatment for HTLV-II-associated neurological disease focuses on managing symptoms and slowing disease progression since there is no cure for the viral infection. Your doctor may prescribe corticosteroids to reduce inflammation in the nervous system, antiviral medications in some cases, and medications to manage muscle spasticity and pain. Physical therapy helps maintain muscle strength and mobility, while occupational therapy assists with daily activities. Bladder management strategies and assistive devices may be needed as symptoms progress.
How can I prevent HTLV-II-associated neurological disease?
You can prevent HTLV-II infection by practicing safe sex using condoms, never sharing needles or injection drug equipment, and screening blood products (now standard in the US since 1988). If you are pregnant and test positive for HTLV-II, avoid breastfeeding to prevent transmission to your baby. Healthcare workers should follow universal precautions when handling blood and body fluids. Getting tested if you have risk factors allows early detection before neurological symptoms develop, enabling prompt monitoring and intervention.
What can I do at home for HTLV-II-associated neurological disease?
At home, maintain an active lifestyle with regular gentle exercise like swimming or water aerobics to preserve muscle strength without overexertion. Use assistive devices like canes or walkers to prevent falls and maintain independence. Apply heat therapy to relieve muscle stiffness and pain. Stay well-hydrated and maintain a nutritious diet rich in anti-inflammatory foods to support overall health. Join support groups to connect with others facing similar challenges, and practice stress-reduction techniques like meditation or yoga to support your nervous system and mental well-being.
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Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation
Google reviews 505 reviews
$287 $224
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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