Autoimmune Thyroid Disease Blood Test

What is Autoimmune Thyroid Disease?

Autoimmune thyroid disease is a condition where the immune system mistakenly attacks the thyroid gland, leading to Hashimoto's thyroiditis or Graves' disease. It is caused by antibodies targeting thyroid tissue, including thyroid peroxidase antibodies (TPO) and thyroglobulin antibodies. The Parietal Cell Antibody ELISA is an essential test for diagnosis because it detects broader autoimmune activity often present alongside thyroid antibodies.

RECOMMENDED TEST Parietal Cell Antibody, ELISA
Google reviews 505 reviews
$363 $283
What's included
Fast & easy, results by email & SMS
No extra fees paid at the lab
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
Why Private MD Labs?
90-day money-back guarantee Lab order in minutes Save a trip to the doctor Low prices since 2005 Labs within 2 miles

What causes autoimmune thyroid disease?

Autoimmune thyroid disease is caused by the immune system producing antibodies that attack the thyroid gland. These antibodies include thyroid peroxidase antibodies (TPO), thyroglobulin antibodies, and thyroid-stimulating immunoglobulins (TSI). The exact trigger for this immune response is not fully understood, but genetic factors, environmental influences, hormonal changes, and certain infections may contribute to the development of these conditions. Women are more likely to develop autoimmune thyroid disease than men, and it often runs in families with a history of autoimmune disorders.

What is the best test for autoimmune thyroid disease?

The Parietal Cell Antibody ELISA is an essential test for autoimmune thyroid disease because it detects antibodies against parietal cells in the stomach, which are frequently found in patients with Hashimoto's thyroiditis and Graves' disease. This test helps identify the broader autoimmune process affecting multiple organ systems beyond just the thyroid. Additionally, thyroid antibody tests measuring TPO antibodies and thyroglobulin antibodies are important for confirming thyroid-specific autoimmune activity. Testing for thyroid-stimulating hormone (TSH), free T4, and free T3 levels provides a complete picture of thyroid function and helps determine whether the autoimmune attack is causing hypothyroidism or hyperthyroidism.

When should I get tested for autoimmune thyroid disease?

You should get tested if you experience unexplained weight changes, persistent fatigue, hair loss, temperature sensitivity, mood changes like anxiety or depression, or irregular menstrual periods. Testing is particularly important if you have a family history of thyroid disease or other autoimmune conditions, or if you notice a visible goiter or swelling in your neck. Early detection through blood testing allows for timely treatment to manage symptoms and prevent complications like heart problems or severe metabolic imbalances.

What are the symptoms of autoimmune thyroid disease?
Symptoms vary depending on whether the condition causes an underactive thyroid (Hashimoto's) or overactive thyroid (Graves' disease). Hashimoto's symptoms include fatigue, weight gain, cold sensitivity, dry skin, constipation, depression, and brain fog. Graves' disease symptoms include weight loss, rapid heartbeat, heat sensitivity, anxiety, tremors, bulging eyes, and difficulty sleeping. Both conditions can cause a goiter (enlarged thyroid), hair loss, muscle weakness, and menstrual irregularities. Some people with autoimmune thyroid disease may have minimal symptoms initially, making blood testing crucial for early detection.
Who is at risk for autoimmune thyroid disease?
Women are five to eight times more likely to develop autoimmune thyroid disease than men, especially during pregnancy, postpartum, and menopause when hormonal fluctuations occur. People with a family history of thyroid disease or other autoimmune conditions like type 1 diabetes, celiac disease, or rheumatoid arthritis face increased risk. Other risk factors include age over 60, previous thyroid problems, radiation exposure to the neck or chest, smoking, excessive iodine intake, and certain viral infections. Individuals with chromosomal disorders like Turner syndrome or Down syndrome also have higher rates of autoimmune thyroid disease.
What happens if autoimmune thyroid disease is left untreated?
Untreated Hashimoto's thyroiditis can lead to severe hypothyroidism, causing heart problems like enlarged heart or heart failure, high cholesterol, infertility, depression, and myxedema coma in extreme cases. Untreated Graves' disease can result in serious complications including irregular heartbeat, stroke, osteoporosis, vision problems or blindness from thyroid eye disease, and thyroid storm, a life-threatening condition with fever and rapid heart rate. Both conditions can significantly impact quality of life, causing persistent fatigue, cognitive difficulties, and emotional instability. Regular monitoring through blood tests and appropriate treatment can prevent these serious complications.
Can autoimmune thyroid disease be diagnosed with a blood test?
Yes, autoimmune thyroid disease is primarily diagnosed through blood tests that detect specific thyroid antibodies and measure thyroid hormone levels. The Parietal Cell Antibody ELISA test identifies broader autoimmune activity often present in patients with thyroid disease. Thyroid antibody tests measuring TPO antibodies, thyroglobulin antibodies, and TSI antibodies confirm autoimmune attack on the thyroid. TSH, free T4, and free T3 tests assess thyroid function to determine if you have hypothyroidism or hyperthyroidism. These blood tests are highly accurate and provide definitive diagnosis without invasive procedures, allowing your doctor to develop an appropriate treatment plan.
How is autoimmune thyroid disease treated?
Hashimoto's thyroiditis is treated with synthetic thyroid hormone replacement medication called levothyroxine, which you take daily to restore normal hormone levels. Graves' disease treatment options include antithyroid medications that reduce hormone production, radioactive iodine therapy that destroys overactive thyroid cells, or surgical removal of part or all of the thyroid gland. Beta-blockers may be prescribed to manage symptoms like rapid heartbeat and tremors while other treatments take effect. Treatment requires regular blood tests to monitor thyroid hormone levels and adjust medication dosages. Most people with autoimmune thyroid disease need lifelong treatment and monitoring to maintain optimal thyroid function.
How can I prevent autoimmune thyroid disease?
While you cannot completely prevent autoimmune thyroid disease, especially if you have genetic predisposition, you can reduce your risk through certain lifestyle measures. Avoid excessive iodine intake from supplements or seaweed, as too much iodine can trigger thyroid problems. Quit smoking, which increases risk for both Hashimoto's and Graves' disease, particularly thyroid eye disease. Manage stress through relaxation techniques, regular exercise, and adequate sleep, as chronic stress can affect immune function. Maintain a balanced diet rich in selenium and vitamin D, which support thyroid health. Regular checkups and blood tests are important if you have family history or other autoimmune conditions.
What natural remedies help with autoimmune thyroid disease?
While natural remedies cannot replace prescribed thyroid medication, certain supplements and lifestyle changes may support thyroid health and reduce inflammation. Selenium supplementation has shown promise in reducing thyroid antibody levels in some studies. Vitamin D, omega-3 fatty acids, and probiotics may help modulate immune function. An anti-inflammatory diet eliminating gluten, processed foods, and excess sugar while emphasizing vegetables, lean proteins, and healthy fats can reduce autoimmune activity. Stress management through yoga, meditation, or tai chi supports immune system balance. Regular gentle exercise improves energy and mood. Always discuss supplements with your healthcare provider, as some can interfere with thyroid medication absorption or effectiveness.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Testosterone 375 ng/dL
Demo results
Normal Optimal 400 - 1000 High
375 ng/dL

What this means

Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

Us vs. Them

Not overhyped or overpriced. Just comprehensive blood testing made simple and for everyone.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

1,000,000+ blood tests later, here's what our customers say

Google reviews 505 reviews Next
Parietal Cell Antibody, ELISA
Google reviews 505 reviews
$363 $283
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

Sample results

Sample image
For you & your coach Health insights Written in human language, backed by science.
Sample image
For you & your doc Classic lab report A familiar and comprehensive lab report.

Ask Me Anything

Your 24/7 Personal Lab Guide

Quick questions:

Which test is right for my symptoms?
What could be causing this?
When should I get tested?
A

Hi, I'm here to make labs simple, clear, and stress-free. Not sure where to start? That's okay. Tell me what's going on and I'll guide you from there.

I can help you:

  • choose the right test
  • prepare for your lab visit
  • take the next step with confidence and more
Just now
A
Not finding what you need? Text 754-799-7833, we've got you.
We provide helpful guidance, not medical diagnoses. For medical decisions, consult a licensed professional.