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Andropause, also called male menopause, is a condition characterized by gradually declining testosterone levels in aging men. It is caused by the natural age-related decrease in testosterone production by the testes, typically beginning after age 40. The Testosterone, Free, LC/MS/MS test is the most important test for diagnosing andropause and determining if hormone replacement therapy is needed.
Andropause is caused by the natural age-related decline in testosterone production by the testes. Starting around age 40, testosterone levels typically decrease by about 1% per year, though the rate varies among men. Unlike female menopause, which happens rapidly, this hormonal decline is gradual and progressive, leading to symptoms that may develop slowly over years.
The Testosterone, Free, LC/MS/MS test is the most important test for andropause because it measures the biologically active form of testosterone that your body actually uses. This advanced test uses highly accurate mass spectrometry technology to detect even small changes in free testosterone levels. Since symptoms of andropause can overlap with other age-related conditions, measuring free testosterone is essential for confirming the diagnosis and determining whether hormone replacement therapy would be beneficial.
You should get tested if you are over 40 and experiencing symptoms like persistent fatigue, decreased sex drive, difficulty achieving erections, mood changes or depression, loss of muscle mass, or increased body fat. Testing is especially important if these symptoms are affecting your quality of life or relationships. Early detection through blood testing allows you to work with your healthcare provider to develop an appropriate treatment plan before symptoms worsen.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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