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Allergies occur when the immune system overreacts to normally harmless substances like pollen, pet dander, dust mites, or certain foods. They are caused by elevated levels of IgE antibodies and immune cells called eosinophils that trigger inflammatory responses when exposed to allergens. The Complete Blood Count with Differential is the most important test for diagnosing allergies because it measures eosinophil levels, which are elevated during allergic reactions.
Allergies are caused by your immune system mistakenly identifying harmless substances as dangerous threats and launching an aggressive defense response. When you encounter an allergen like pollen, pet dander, dust mites, mold, or certain foods, your body produces IgE antibodies that trigger immune cells called mast cells and eosinophils to release inflammatory chemicals like histamine. This cascade of immune reactions causes the classic allergy symptoms you experience, from sneezing and itchy eyes to hives and digestive problems, depending on where in your body the allergic reaction occurs.
The Complete Blood Count with Differential is the most important test for allergies because it measures eosinophil levels, which are specialized white blood cells that increase dramatically during allergic reactions. Elevated eosinophils directly indicate your immune system is responding to allergens. For a comprehensive evaluation, the Histamine Release test is also essential as it measures the primary chemical that causes allergy symptoms like itching, hives, and swelling when mast cells react to allergens. The Interleukin-4 test can provide deeper insight by measuring IL-4, a key immune regulator that stimulates IgE antibody production and drives the allergic inflammatory response.
You should get tested if you experience recurring symptoms like sneezing, runny nose, itchy or watery eyes, skin rashes, hives, or digestive issues that seem to appear after exposure to certain foods, environments, or seasons. Testing is particularly important if over-the-counter allergy medications are not providing relief, if your symptoms are interfering with your daily activities or sleep, or if you have frequent sinus infections or asthma that might be triggered by allergies. Getting tested helps identify what you are allergic to so you can avoid triggers and find the right treatment approach.
What this means
Your testosterone levels are slightly below the optimal range. While this is not necessarily cause for concern, it may contribute to occasional fatigue, reduced motivation, or lower muscle mass over time.
Recommended actions
Increase resistance or strength training
Prioritize 7–8 hours of quality sleep per night, try to reduce stress
Include more zinc- and magnesium-rich foods (like shellfish, beef, pumpkin seeds, spinach)
Consider retesting in 3–6 months
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