Allergic Disease Blood Test

What is Allergic Disease?

Allergic disease is a condition where the immune system overreacts to normally harmless substances called allergens, triggering symptoms in the respiratory system, skin, or digestive tract. It is caused by elevated production of Immunoglobulin E (IgE) antibodies in response to specific environmental triggers like pollen, mold, pet dander, or dust mites. The Respiratory Allergy Profile is the most important test for diagnosis because it measures IgE levels specific to regional allergens causing your symptoms.

RECOMMENDED TEST Respiratory Allergy Profile Region XVIII: Alaska
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What causes allergic disease?

Allergic disease is caused by an overactive immune response to substances that are normally harmless to most people. When you encounter an allergen like pollen, mold spores, pet dander, dust mites, or certain foods, your immune system mistakenly identifies it as a threat and produces Immunoglobulin E (IgE) antibodies. These antibodies trigger the release of histamine and other chemicals from immune cells, leading to the classic allergy symptoms like sneezing, itching, hives, swelling, congestion, and in severe cases, difficulty breathing. The tendency to develop allergies often runs in families, and environmental factors like pollution and early childhood exposures can influence whether you develop allergic sensitivities.

What is the best test for allergic disease?

The Respiratory Allergy Profile is the most important test for allergic disease because it measures specific IgE antibody levels in response to common environmental allergens in your geographic region. This blood test identifies exactly which substances trigger your immune system, whether they are tree pollens, grass pollens, mold spores, dust mites, or animal dander. The test provides precise quantitative measurements of your IgE levels for each allergen, helping you and your healthcare provider understand which exposures to avoid and which treatments will be most effective. Unlike skin prick tests, blood testing is not affected by antihistamine medications and is safer for people with severe skin conditions or a history of anaphylaxis. Regional-specific panels are especially valuable because they focus on the allergens you are most likely to encounter in your local environment.

When should I get tested for allergic disease?

You should get tested if you experience recurring symptoms like sneezing, runny or stuffy nose, itchy or watery eyes, skin rashes, hives, or difficulty breathing, especially if these symptoms appear during certain seasons or after exposure to specific environments. Testing is particularly important if over-the-counter allergy medications are not providing adequate relief, if you are unsure which allergens are triggering your symptoms, or if you are considering immunotherapy (allergy shots). You should also get tested if your symptoms interfere with your daily activities, sleep, or quality of life, or if you have asthma that seems to worsen with environmental exposures. Early identification of your specific allergens allows you to make targeted lifestyle changes and work with your doctor on a personalized treatment plan.

What are the symptoms of allergic disease?
Allergic disease symptoms vary depending on which part of your body is affected by the allergic reaction. Respiratory allergies cause sneezing, runny or congested nose, itchy or watery eyes, coughing, wheezing, and shortness of breath. Skin allergies produce hives, rashes, itching, redness, swelling, and eczema flare-ups. Food allergies can trigger digestive symptoms like nausea, vomiting, diarrhea, and stomach cramps, along with skin reactions and respiratory issues. Some people experience mild symptoms that are merely annoying, while others have severe reactions that significantly impact their daily functioning. In rare cases, allergies can cause anaphylaxis, a life-threatening reaction involving difficulty breathing, rapid pulse, dizziness, and loss of consciousness that requires immediate emergency treatment.
Who is at risk for allergic disease?
You are at higher risk for developing allergic disease if you have a family history of allergies, asthma, or eczema, as genetic factors play a significant role in allergic tendencies. Children are particularly susceptible, though allergies can develop at any age. People with existing allergic conditions like hay fever or food allergies are more likely to develop additional sensitivities. Environmental factors also matter: exposure to tobacco smoke, air pollution, and certain chemicals can increase your risk. Living in developed countries and urban areas, having fewer childhood infections, and being exposed to fewer microbes in early life may contribute to higher allergy rates due to the hygiene hypothesis. People with compromised immune systems or chronic inflammatory conditions may also have increased susceptibility to developing allergic diseases.
What happens if allergic disease is left untreated?
Untreated allergic disease can significantly impact your quality of life and lead to serious complications over time. Chronic nasal allergies can progress to sinus infections, ear infections, and the development of nasal polyps. Persistent allergic inflammation in the airways can trigger or worsen asthma, leading to breathing difficulties and potentially dangerous asthma attacks. Sleep disruption from nighttime allergy symptoms can cause fatigue, decreased productivity, and mood problems. Skin allergies left unmanaged often result in chronic scratching, skin infections, and permanent skin changes. Long-term exposure to allergens without treatment keeps your immune system in a constant state of inflammation, which can affect your overall health and well-being. In some cases, repeated exposures to allergens can lead to increasingly severe reactions, making early identification and management crucial for preventing complications.
Can allergic disease be diagnosed with a blood test?
Yes, allergic disease can be effectively diagnosed with blood tests that measure Immunoglobulin E (IgE) antibodies specific to various allergens. These blood tests are highly accurate and offer several advantages over traditional skin prick tests. Blood testing is not affected by antihistamines or other medications you may be taking, can be performed safely even if you have severe eczema or skin conditions, and carries no risk of triggering an allergic reaction during testing. The test requires only a simple blood draw and can screen for dozens of allergens simultaneously. Results provide quantitative measurements showing not just whether you are allergic, but how strongly you react to each specific allergen. This detailed information helps your healthcare provider create a targeted treatment plan and gives you clear guidance on which environmental exposures to avoid for the best symptom control.
How is allergic disease treated?
Allergic disease treatment typically involves a three-pronged approach: allergen avoidance, medications, and in some cases, immunotherapy. The first step is identifying and minimizing exposure to your specific triggers through environmental controls like using air purifiers, keeping windows closed during high pollen seasons, regularly washing bedding, and reducing indoor humidity to control dust mites and mold. Medications include antihistamines to block allergic reactions, nasal corticosteroid sprays to reduce inflammation, decongestants for congestion relief, and leukotriene modifiers for asthma and allergies. For people with moderate to severe allergies that do not respond adequately to avoidance and medications, allergen immunotherapy (allergy shots or sublingual tablets) can be highly effective by gradually desensitizing your immune system to specific allergens. Your healthcare provider will customize your treatment plan based on your specific allergens, symptom severity, and lifestyle factors.
How can I prevent allergic disease?
While you cannot completely prevent the development of allergic tendencies, especially if you have a genetic predisposition, you can take steps to reduce your risk and minimize allergic reactions. For infants at high risk, breastfeeding for at least six months and introducing potential allergenic foods early under medical guidance may help prevent food allergies. Maintaining a clean but not sterile home environment, allowing children to play outdoors and interact with pets, and avoiding unnecessary antibiotic use may support healthy immune system development. To prevent allergic reactions once sensitivities develop, monitor pollen counts and stay indoors on high-pollen days, use HEPA air filters in your home and car, wash hands and face after being outdoors, shower before bed to remove allergens from hair and skin, keep humidity levels below 50 percent to discourage dust mites and mold, and encase mattresses and pillows in allergen-proof covers. Regular cleaning and removing clutter where dust accumulates also helps reduce indoor allergen levels.
What natural remedies help with allergic disease?
Several natural approaches can complement medical treatment for allergic disease, though they should not replace prescribed medications for moderate to severe symptoms. Nasal saline rinses or neti pots help flush allergens and mucus from nasal passages, reducing congestion and irritation. Local honey consumed regularly may help build tolerance to local pollens, though scientific evidence is mixed. Quercetin, a natural plant compound found in apples, onions, and tea, has antihistamine properties that some people find helpful. Butterbur extract has shown promise in studies for reducing hay fever symptoms. Probiotics may support immune system balance and reduce allergic inflammation. Omega-3 fatty acids from fish oil have anti-inflammatory effects that can help with allergic responses. Keeping windows closed during peak pollen times, using a damp cloth to dust, and removing shoes at the door prevents allergen accumulation in your home. Steam inhalation can provide temporary relief from congestion. Always discuss natural remedies with your healthcare provider, as some can interact with medications or may not be safe for everyone.
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Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

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Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
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If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Respiratory Allergy Profile Region XVIII: Alaska
Google reviews 505 reviews
$887 $692
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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