Fungal Lung Allergy Blood Test

What is Allergic Bronchopulmonary Mycosis?

Allergic bronchopulmonary mycosis is a severe allergic reaction in the lungs caused by breathing in fungal spores, leading to wheezing, fever, and persistent cough with mucus. It is caused by hypersensitivity to fungal organisms, most commonly Alternaria alternata and Aspergillus fumigatus, which trigger an intense immune response in the airways. The Respiratory Allergy Panel Region III is the most important test for identifying specific fungal allergens triggering this condition.

RECOMMENDED TEST Respiratory Allergy Panel Region III: GA, northern FL, SC
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What causes allergic bronchopulmonary mycosis?

Allergic bronchopulmonary mycosis is caused by an exaggerated immune response to fungal spores that are inhaled into the lungs, particularly Alternaria alternata and Aspergillus fumigatus. When these fungal organisms colonize the airways, your immune system overreacts, releasing inflammatory chemicals that cause the bronchial tubes to swell and produce excess mucus. This condition typically develops in people who already have asthma or cystic fibrosis, as their airways are more vulnerable to fungal colonization and allergic reactions.

What is the best test for allergic bronchopulmonary mycosis?

The Respiratory Allergy Panel Region III is the most important test for allergic bronchopulmonary mycosis because it specifically detects IgE antibodies to fungal allergens including Alternaria alternata, which is a primary trigger of this condition. This comprehensive panel measures your immune system's allergic response to various mold and fungal spores that commonly cause respiratory allergies. The test identifies which specific fungi you are sensitized to, allowing your healthcare provider to confirm the diagnosis and develop a targeted treatment plan to reduce your exposure to these triggers and manage your symptoms effectively.

When should I get tested for allergic bronchopulmonary mycosis?

You should get tested if you have asthma or cystic fibrosis and experience worsening symptoms like persistent wheezing, coughing up brown mucus plugs, unexplained fever, or breathing problems that do not improve with standard asthma medications. Testing is especially important if you notice your symptoms flare up during humid weather or in damp environments where mold grows. Early diagnosis through allergy testing helps prevent permanent lung damage and allows for prompt treatment to control the allergic inflammation before it causes scarring in your airways.

What are the symptoms of allergic bronchopulmonary mycosis?
The most common symptoms include persistent wheezing, shortness of breath, low-grade fever, general malaise, and coughing up thick brown or blood-tinged mucus plugs. Many people also experience chest discomfort, worsening asthma symptoms that do not respond well to inhalers, and fatigue. As the condition progresses, you might notice decreased exercise tolerance and recurring lung infections. The symptoms often worsen during humid weather or in environments with high mold exposure, such as damp basements or areas with water damage.
Who is at risk for allergic bronchopulmonary mycosis?
People with asthma and cystic fibrosis are at highest risk for developing allergic bronchopulmonary mycosis, as their compromised airways provide an environment where fungal spores can colonize more easily. Individuals with weakened immune systems, those living in humid climates or moldy environments, and people with chronic lung diseases also face increased risk. The condition most commonly affects adults between 20 and 40 years old, though it can occur at any age. If you have a family history of allergic conditions or take immunosuppressive medications, your risk is also elevated.
What happens if allergic bronchopulmonary mycosis is left untreated?
Untreated allergic bronchopulmonary mycosis can lead to permanent lung damage and scarring called bronchiectasis, where the airways become irreversibly widened and damaged. This chronic inflammation causes the airways to lose their ability to clear mucus effectively, leading to repeated infections and progressive breathing difficulty. Over time, the condition can result in respiratory failure, pulmonary fibrosis, and significantly reduced lung function. Early diagnosis and treatment are essential to prevent these serious complications and preserve your lung health for the long term.
Can allergic bronchopulmonary mycosis be diagnosed with a blood test?
Blood tests play an important supporting role in diagnosing allergic bronchopulmonary mycosis by detecting specific IgE antibodies to fungal allergens like Alternaria alternata and Aspergillus fumigatus. The Respiratory Allergy Panel measures your immune response to these fungi and helps confirm allergic sensitization. However, diagnosis requires a combination of blood test results, imaging studies showing lung infiltrates, elevated total IgE levels, and clinical symptoms consistent with the condition. Your healthcare provider will interpret the blood test results along with chest X-rays or CT scans and your medical history to make a definitive diagnosis.
How is allergic bronchopulmonary mycosis treated?
Treatment typically involves oral corticosteroids like prednisone to reduce the allergic inflammation in your lungs and prevent permanent damage. Your doctor may also prescribe antifungal medications such as itraconazole to reduce the fungal burden in your airways and prevent colonization. Asthma medications including inhaled corticosteroids and bronchodilators help control breathing symptoms and keep airways open. Long-term management focuses on monitoring lung function regularly, avoiding mold exposure, using dehumidifiers in your home, and maintaining good asthma control to prevent flare-ups and complications.
How can I prevent allergic bronchopulmonary mycosis?
Prevention focuses on reducing your exposure to mold and fungal spores that trigger the condition. Keep indoor humidity below 50 percent using dehumidifiers, fix water leaks promptly, and ensure proper ventilation in bathrooms and kitchens. Clean moldy surfaces with bleach solutions, avoid raking leaves or working with compost if you have asthma, and use HEPA air filters in your home. If you have asthma or cystic fibrosis, maintain excellent control of your underlying condition with prescribed medications and regular check-ups to reduce your susceptibility to fungal colonization.
What can I do at home for allergic bronchopulmonary mycosis?
At home, focus on creating a mold-free environment by controlling humidity levels, fixing leaks immediately, and cleaning damp areas regularly. Use allergen-proof covers on mattresses and pillows, wash bedding weekly in hot water, and avoid carpeting in bedrooms where you spend the most time. Practice good asthma hygiene by taking medications as prescribed, using a peak flow meter to monitor breathing, and keeping windows closed during high mold spore seasons. Stay hydrated to help thin mucus secretions, and consider using a saline nasal rinse to clear fungal spores from your nasal passages before they reach your lungs.
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Respiratory Allergy Panel Region III: GA, northern FL, SC
Google reviews 505 reviews
$1,207 $941
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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