Acute Leukemia Blood Test

What is Acute Leukemia?

Acute leukemia is a rapidly progressing cancer of the blood and bone marrow that requires immediate medical attention. It is caused by the uncontrolled production of abnormal white blood cells called blast cells that crowd out healthy blood cells in the bone marrow. The Complete Blood Count (CBC) with Differential and Platelets is the most important test for initial diagnosis because it detects the presence of blast cells and reveals abnormal blood cell counts characteristic of acute leukemia.

RECOMMENDED TEST Complete Blood Count / CBC (includes Differential and Platelets)
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What causes acute leukemia?

Acute leukemia is caused by genetic mutations in bone marrow cells that lead to the uncontrolled production of abnormal white blood cells called blast cells. These immature cells multiply rapidly and cannot perform normal immune functions, crowding out healthy red blood cells, white blood cells, and platelets. While the exact trigger for these mutations is often unknown, risk factors include previous chemotherapy or radiation treatment, certain genetic disorders like Down syndrome, exposure to high levels of radiation or chemicals like benzene, and some viral infections.

What is the best test for acute leukemia?

The Complete Blood Count (CBC) with Differential and Platelets is the most important initial test for acute leukemia because it detects the hallmark sign of this cancer: the presence of blast cells (immature white blood cells) in the bloodstream. This comprehensive blood panel measures all blood cell types and reveals characteristic abnormalities including elevated white blood cell counts with immature cells, low red blood cell counts causing anemia, and low platelet counts increasing bleeding risk. The CBC provides crucial screening information that guides your doctor toward additional confirmatory tests like bone marrow biopsy and genetic testing to determine the specific type of acute leukemia and develop a treatment plan.

When should I get tested for acute leukemia?

You should get tested if you experience persistent fatigue and weakness that doesn't improve with rest, frequent infections or fevers, easy bruising or bleeding including nosebleeds or bleeding gums, unexplained weight loss, or bone and joint pain. Additionally, seek testing if you notice pale skin, shortness of breath, enlarged lymph nodes, or small red spots under the skin called petechiae. Because acute leukemia develops rapidly, prompt testing is critical when multiple symptoms appear together or worsen quickly over days to weeks rather than months.

What are the symptoms of acute leukemia?
Acute leukemia symptoms develop rapidly and include extreme fatigue and weakness, frequent infections and fevers, easy bruising and bleeding, pale skin from anemia, shortness of breath, bone and joint pain, swollen lymph nodes in the neck or groin, and unexplained weight loss. You might also notice small red spots under the skin called petechiae, persistent nosebleeds, bleeding gums, heavy menstrual periods, or night sweats. Some people experience abdominal discomfort from an enlarged spleen or liver. These symptoms occur because abnormal blast cells crowd out healthy blood cells that normally fight infections, carry oxygen, and help blood clot properly.
Who is at risk for acute leukemia?
People at higher risk for acute leukemia include those previously treated with chemotherapy or radiation therapy for other cancers, individuals with genetic disorders like Down syndrome or Li-Fraumeni syndrome, and those with certain blood disorders such as myelodysplastic syndrome. Exposure to high levels of radiation or industrial chemicals like benzene increases risk, as does smoking. While acute leukemia can occur at any age, acute lymphoblastic leukemia (ALL) is most common in young children under age 5, while acute myeloid leukemia (AML) primarily affects adults over 65. Having a sibling with leukemia, particularly an identical twin, also increases risk.
What happens if acute leukemia is left untreated?
Untreated acute leukemia progresses rapidly and becomes life-threatening within weeks to months because blast cells continue multiplying and crowding out healthy blood cells. You face severe, potentially fatal infections due to lack of functional white blood cells, life-threatening bleeding from critically low platelet counts, and organ damage as leukemia cells infiltrate the liver, spleen, lymph nodes, and potentially the brain and spinal fluid. Severe anemia causes heart problems as your body struggles to deliver oxygen to vital organs. The bone marrow becomes so packed with abnormal cells that production of all healthy blood cells stops completely. Acute leukemia is a medical emergency that requires immediate treatment to prevent these devastating complications.
Can acute leukemia be diagnosed with a blood test?
A Complete Blood Count (CBC) with Differential can strongly suggest acute leukemia by detecting blast cells in the bloodstream and revealing abnormal blood cell counts, but blood tests alone cannot definitively diagnose the condition. The CBC serves as the critical first screening tool that identifies suspicious findings requiring further investigation. If your blood test shows blast cells or concerning abnormalities, your doctor will order a bone marrow biopsy to confirm the diagnosis, determine the specific type of acute leukemia (lymphoblastic or myeloid), and guide treatment decisions. Additional specialized tests including cytogenetic analysis, flow cytometry, and molecular testing are performed on bone marrow samples to fully characterize the leukemia.
How is acute leukemia treated?
Acute leukemia is treated with intensive chemotherapy as the primary approach, typically delivered in phases including induction therapy to achieve remission, consolidation therapy to eliminate remaining cancer cells, and sometimes maintenance therapy for long-term control. Treatment may include targeted therapy drugs that attack specific genetic mutations in leukemia cells, immunotherapy to help your immune system recognize and destroy cancer cells, and stem cell transplantation (bone marrow transplant) for high-risk cases or relapsed disease. Radiation therapy is sometimes used for leukemia that has spread to the brain or spinal fluid. Treatment is highly individualized based on the specific type of acute leukemia, genetic characteristics of the cancer cells, your age, and overall health.
How can I prevent acute leukemia?
Most cases of acute leukemia cannot be prevented because the genetic mutations that cause it occur randomly without known preventable triggers. However, you can reduce some risk factors by avoiding tobacco smoke, which increases acute myeloid leukemia risk, limiting exposure to industrial chemicals like benzene and formaldehyde through proper workplace safety measures, and minimizing unnecessary radiation exposure. If you require chemotherapy or radiation for another cancer, discuss the long-term leukemia risk with your oncologist, though the benefits of treating the primary cancer typically far outweigh this risk. People with genetic predispositions or blood disorders should maintain regular medical monitoring for early detection.
What can I do at home to support acute leukemia treatment?
While acute leukemia requires intensive medical treatment and cannot be managed at home alone, you can support your treatment by preventing infections through frequent handwashing, avoiding crowds and sick people, practicing good dental hygiene, and cooking food thoroughly. Manage fatigue by balancing rest with gentle activity as tolerated, eating small frequent meals with adequate protein and calories to maintain strength, and staying well-hydrated. Prevent bleeding by using soft toothbrushes, avoiding contact sports and sharp objects, and reporting any unusual bruising or bleeding immediately. Work closely with your healthcare team, attend all appointments, take medications exactly as prescribed, and communicate openly about side effects and concerns throughout your treatment journey.
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Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

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Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
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We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
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During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
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Complete Blood Count / CBC (includes Differential and Platelets)
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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