This test is ideal if your baby is experiencing persistent digestive problems, feeding difficulties, slow growth, or unusual fussiness that might be related to gluten sensitivity. It helps identify celiac disease early, which is an immune reaction to gluten that can interfere with nutrient absorption and your baby's development. Many parents use this test when their infant has unexplained symptoms that started after introducing solid foods containing wheat, barley, or rye.
How should I prepare for this test?
Your infant should be consuming gluten-containing foods regularly before testing for accurate results. Do not start a gluten-free diet before the test, as this can cause false negatives. The test requires a blood draw, which can be done at any convenient lab location. No fasting is typically required for infants, but confirm with your lab location when scheduling.
What's included in this test?
This panel evaluates three key markers that detect celiac disease in infants. It measures tissue transglutaminase antibodies (tTG IgA), which are highly specific for celiac disease, and gliadin antibodies (IgA), which help identify gluten reactions. It also checks total IgA levels because some infants naturally have low IgA, which can affect test accuracy. Together, these measurements provide a comprehensive picture of whether your baby's immune system is reacting to gluten.
What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your infant's antibody levels mean and whether gluten sensitivity is likely. These notes include personalized recommendations like whether to try a gluten-free diet, when to consult a pediatric gastroenterologist, or if further testing is needed. You'll also get the standard lab report and can track your baby's levels over time using our trends feature, which is especially helpful if monitoring dietary changes or confirming diagnosis.
Who should consider getting this test?
This test is recommended for infants showing signs of digestive issues like chronic diarrhea, constipation, bloating, or poor weight gain after introducing gluten-containing foods. It's also important for babies with a family history of celiac disease, Type 1 diabetes, or other autoimmune conditions. Consider testing if your infant seems unusually irritable, has feeding difficulties, or shows developmental delays that might be related to nutrient malabsorption.
What symptoms indicate my baby may need this test?
Watch for persistent digestive symptoms like frequent diarrhea, unusually smelly or pale stools, bloating, or gas after eating foods with wheat or barley. Growth concerns like slow weight gain, poor appetite, or failure to thrive are important warning signs. Other symptoms include excessive fussiness, irritability, fatigue, or a swollen belly. Some infants may also develop a skin rash or seem to have recurring tummy pain.
How can I manage my baby's diet if gluten sensitivity is suspected?
If celiac disease is confirmed, you'll need to eliminate all gluten-containing foods including wheat, barley, rye, and contaminated oats from your baby's diet. Focus on naturally gluten-free foods like rice cereal, fruits, vegetables, meat, eggs, and dairy. Work with a pediatric dietitian to ensure your infant gets proper nutrition and learns which packaged foods are safe. Read labels carefully, as gluten hides in many processed foods.
What is celiac disease and why does early detection matter?
Celiac disease is an autoimmune condition where eating gluten triggers the immune system to attack the small intestine, damaging the lining and preventing nutrient absorption. In infants, this can seriously impact growth, development, and overall health if left untreated. Early detection is crucial because untreated celiac disease can lead to malnutrition, delayed development, and long-term complications. The good news is that once diagnosed, most infants thrive on a gluten-free diet.
What does it mean if my baby's tTG antibodies are elevated?
Elevated tissue transglutaminase (tTG) antibodies strongly suggest that your baby's immune system is reacting to gluten, which is a hallmark of celiac disease. High levels indicate active intestinal damage from gluten exposure. Your pediatrician may recommend confirmation with an intestinal biopsy or consultation with a pediatric gastroenterologist. The good news is that with a strict gluten-free diet, these antibodies typically decrease and the intestine can heal.
How often should I retest my infant if results are abnormal?
If your baby is diagnosed with celiac disease and starts a gluten-free diet, your doctor will typically retest antibody levels every 3-6 months to monitor how well the treatment is working. Antibody levels should gradually decrease on a strict gluten-free diet, showing that the intestine is healing. Once levels stabilize in the normal range, annual testing is common to ensure continued dietary compliance and monitor your child's health as they grow.
How’s this work?
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Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
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Your infant's tTG antibody level is elevated, which suggests an immune reaction to gluten that is characteristic of celiac disease. This means your baby's body is producing antibodies that attack the small intestine when gluten is consumed, which can interfere with nutrient absorption and healthy growth.
Recommended actions
Consult with a pediatric gastroenterologist for confirmation and dietary guidance
Do not start a gluten-free diet until diagnosis is confirmed, as it may affect future testing
Keep a food diary to track symptoms and identify gluten-containing foods
Work with a pediatric dietitian to plan a safe, nutritious gluten-free diet if diagnosis is confirmed
* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Order your testSave a trip to the doctor. Your results will come with clear, friendly explanations.Takes 2 minutes
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Get resultsReceive a clear, easy-to-digest health report by email & SMS within a few business days.Get answers, fast
Celiac Disease Test for Infants with Digestive Issues
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Pinpoint gluten sensitivity causing your baby's discomfort
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