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Comprehensive adrenal and stress hormone test for fatigue and unexplained weight changes

Blood Test for Fatigue and Adrenal Function

Addison's Disease Screen (Basic)

  • Pinpoint the cause of your fatigue
  • Reveal hidden adrenal issues effortlessly
  • Clarify unexplained weight loss or gain
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing persistent fatigue, unexplained weight loss or gain, dizziness, low blood pressure, or darkening of the skin. It helps identify Addison's disease, a condition where your adrenal glands don't produce enough essential hormones like cortisol. Many people use this test when they have symptoms that suggest their body isn't managing stress and energy properly.

How should I prepare for this test?

Fasting: 12 hours

You should fast for 12 hours before your blood draw. The ACTH portion must be drawn between 7 AM and 10 AM for accurate results, as hormone levels vary throughout the day. If you're taking prednisone or prednisolone, discuss this with your doctor beforehand as these medications can interfere with cortisol testing. If you're on diuretics or certain other medications that affect uric acid, talk to your physician about temporarily stopping them before testing.

What's included in this test?

Acth, Plasma Cortisol, Total Magnesium Uric Acid

This comprehensive panel measures ACTH and cortisol levels to evaluate how well your adrenal glands are producing stress hormones, along with adrenal antibodies that can indicate autoimmune causes. It includes a complete metabolic profile to check electrolyte imbalances (sodium, potassium, chloride) commonly seen in adrenal insufficiency, a complete blood count to assess overall health, urinalysis to monitor kidney function, and additional markers like magnesium and uric acid. Together, these measurements provide a complete picture of adrenal function and help identify whether your symptoms are related to hormone deficiency.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your adrenal hormone levels and related markers mean for your energy, stress response, and overall health. These notes include personalized recommendations like lifestyle adjustments, when to seek endocrinology care, or if hormone replacement therapy might be needed. You'll also get the standard lab report and can track your adrenal function over time using our trends feature to monitor how treatments or lifestyle changes are working.
When will I get my results?
You can expect to receive your results within 10 business days. Some tests in this panel may require confirmation testing if initial results are abnormal, which could extend the turnaround time. You'll be notified if additional testing is needed, and your comprehensive results will include all necessary follow-up information.
Who should consider getting this test?
This test is important for people experiencing chronic fatigue, weakness, weight loss, low blood pressure, or salt cravings that don't have an obvious cause. It's also valuable for those with darkening skin patches, frequent dizziness when standing, or a family history of autoimmune conditions. Anyone who has been told their symptoms might be stress-related but hasn't found relief should consider this comprehensive adrenal evaluation.
What symptoms indicate I may need this test?
Common symptoms include extreme and persistent fatigue that doesn't improve with rest, unintentional weight loss, muscle weakness, low blood pressure that causes dizziness, and increased skin pigmentation especially in skin folds. You might also experience salt cravings, nausea, digestive issues, irritability, or depression. These symptoms often develop gradually and worsen during times of physical stress or illness.
How can I naturally support my adrenal health?
Supporting adrenal health involves managing stress through practices like meditation, deep breathing, or gentle yoga. Prioritize 7-9 hours of quality sleep each night and maintain stable blood sugar by eating regular, balanced meals with adequate protein and healthy fats. Include foods rich in vitamin C, B vitamins, and magnesium like citrus fruits, leafy greens, nuts, and whole grains. However, if you have Addison's disease, natural approaches alone are not sufficient and hormone replacement therapy is necessary.
What is cortisol and why does it matter?
Cortisol is your body's main stress hormone, produced by your adrenal glands. It helps regulate your metabolism, blood sugar, blood pressure, immune response, and how your body responds to stress. When cortisol levels are too low, as in Addison's disease, your body can't properly manage stress, maintain energy, or regulate important functions like blood pressure and inflammation, leading to the fatigue and weakness people experience.
What does low cortisol mean?
Low cortisol levels can indicate that your adrenal glands aren't producing enough of this essential hormone, which is the hallmark of Addison's disease or adrenal insufficiency. This can cause persistent fatigue, weakness, weight loss, low blood pressure, and difficulty handling physical or emotional stress. Low cortisol is serious and typically requires medical treatment with hormone replacement therapy to prevent potentially dangerous complications during illness or stress.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Cortisol, Total 4.2 mcg/dL
Demo results
Low Optimal 6.0 - 18.0 High
4.2 mcg/dL

What this means

Your cortisol level is below the optimal range, which may indicate that your adrenal glands aren't producing enough of this essential stress hormone. Low cortisol can explain symptoms like persistent fatigue, weakness, difficulty handling stress, and low blood pressure. This finding warrants further evaluation to determine if adrenal insufficiency or Addison's disease may be present.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Fatigue and Adrenal Function

  • Pinpoint the cause of your fatigue
  • Reveal hidden adrenal issues effortlessly
  • Clarify unexplained weight loss or gain
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.

Ask Me Anything

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Quick questions:

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We provide helpful guidance, not medical diagnoses. For medical decisions, consult a licensed professional.